Journal of Cranio-Maxillo-Facial Surgery
Volume 38, Issue 4 , Pages 266-270 , June 2010

Head and neck lesions of Kimura's disease: Exclusion of human herpesvirus-8 and Epstein-Barr virus by in situ hybridisation and polymerase chain reaction. An immunohistochemical study

  • Poramate Pitak-Arnnop, D.D.S., M.Sc.

      Affiliations

    • Department of Maxillofacial Surgery (Head: Prof. Jacques-Charles Bertrand M.D.), AP-HP, Pitié-Salpêtrière University Hospital Faculty of Medicine, University Paris 6 (Pierre et Marie Curie), Paris, France
    • Department of Oral, Craniomaxillofacial and Facial Plastic Surgery (Head: Prof. Alexander Hemprich M.D., D.M.D., Ph.D.), Faculty of Medicine, University Hospital of Leipzig, Leipzig, Germany
    • Laboratory of Medical Ethics and Legal Medicine (Head: Prof. Christian Hervé M.D., Ph.D.), Faculty of Medicine, University Paris 5 (René Descartes), Paris, France
    • Corresponding Author InformationDr. Poramate PITAK-ARNNOP, D.D.S., M.Sc, Klinik und Poliklinik für Mund-, Kiefer- und Plastische Gesichtschirurgie, Universitätsklinikum Leipzig AöR, Nürnberger Str. 57, 04103 Leipzig, Germany. Tel.: +49 341 97 21 100 Fax: +49 341 97 21 109
    • ,
  • Salima Bellefqih, M.D., M.Sc.

      Affiliations

    • Laboratory Pol Bouin, Department of Embryology, Cytology, Pathology and Molecular Biology (Head: Prof. Philippe Birembaut M.D.), Faculty of Medicine, Maison Blanche University Hospital, Reims, France; Formerly, Department of Anatomical and Cytological Pathology (Head: Prof. Frédérique Capron M.D., Ph.D.), AP-HP, Pitié-Salpêtrière University Hospital, Faculty of Medicine, University Paris 6 (Pierre et Marie Curie), Paris, France
    • ,
  • André Chaine, M.D.

      Affiliations

    • Department of Maxillofacial Surgery (Head: Prof. Jacques-Charles Bertrand M.D.), AP-HP, Pitié-Salpêtrière University Hospital Faculty of Medicine, University Paris 6 (Pierre et Marie Curie), Paris, France
    • ,
  • Kittipong Dhanuthai, D.D.S., M.Sc.

      Affiliations

    • Department of Oral Pathology (Head: Assoc. Prof. Somporn Swasdison D.D.S., Ph.D.), Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand
    • ,
  • Jacques-Charles Bertrand, M.D.

      Affiliations

    • Department of Maxillofacial Surgery (Head: Prof. Jacques-Charles Bertrand M.D.), AP-HP, Pitié-Salpêtrière University Hospital Faculty of Medicine, University Paris 6 (Pierre et Marie Curie), Paris, France
    • ,
  • Chloé Bertolus, M.D., M.Sc.

      Affiliations

    • Department of Maxillofacial Surgery (Head: Prof. Jacques-Charles Bertrand M.D.), AP-HP, Pitié-Salpêtrière University Hospital Faculty of Medicine, University Paris 6 (Pierre et Marie Curie), Paris, France

Received 9 November 2008 ,Accepted 19 August 2009.

References 

  1. Armstrong WB, Allison G, Pena F, Kim JK. Kimura's disease: two case reports and a literature review. Ann Otol Rhinol Laryngol. 1998;107:1066–1071
  2. Bienz KA. Herpesviruses. In:  Kayser FH,  Bienz KA,  Eckert J,  Zinkernagel RM editor. Medical microbiology. Stuttgart: Thieme; 2005;p. 418–426
  3. Boshoff C, Schulz TF, Kennedy MM, Graham AK, Fisher C, Thomas A, et al. Kaposi's sarcoma associated herpesvirus infects endothelial and spindle cells. Nat Med. 1995;1:1274–1278
  4. Chen H, Thompson LD, Aguilera NS, Abbondanzo SL. Kimura disease: a clinicopathologic study of 21 cases. Am J Surg Pathol. 2004;28:505–513
  5. Chim CS, Shek TW, Liang R, Kwong YL. Kimura's disease: no evidence of clonality. Br J Ophthalmol. 1999;83:880–881
  6. Chim CS, Liang R, Fung A, Kwong YL, Shek TW. Further Analysis of clonality in Kimura's Disease. Am J Surg Pathol. 2003;27:703–704
  7. Chitapanarux I, Ya-in C, Kittichest R, Kamnerdsupaphon P, Lorvidhaya V, Sukthomya V, et al. Radiotherapy in Kimura's disease: a report of eight cases. J Med Assoc Thai. 2007;90:1001–1005
  8. Day TA, Abreo F, Hoajsoe DK, Aarstad RF, Stucker FJ. Treatment of Kimura's disease: a therapeutic enigma. Otolaryngol Head Neck Surg. 1995;112:333–337
  9. Dhanuthai K, Jansisyanont P, Tangjaturonrasami P, Amornpitakpunt K. Kimura's disease. Asian J Oral Maxillofac Surg. 2006;18:151–156
  10. Dupin N, Diss TL, Kellam P, Tulliez M, Du MQ, Sicard D, et al. HHV-8 is associated with a plasmablastic variant of Castleman disease that is linked to HHV-8-positive plasmablastic lymphoma. Blood. 2000;95:1406–1412
  11. Googe PB, Harris NL, Mihm MC. Kimura's disease and angiolymphoid hyperplasia with eosinophilia: two distinct histopathological entities. J Cutan Pathol. 1987;14:263–271
  12. Gumbs MA, Pai NB, Saraiya RJ, Rubinstein J, Vythilingam L, Choi YJ. Kimura's disease: a case report and literature review. J Surg Oncol. 1999;70:190–193
  13. Gyulai R, Kemény L, Adàm E, Nagy F, Dobozy A. HHV8 DNA in angiolymphoid hyperplasia of the skin. Lancet. 1996;347:1837
  14. Hengge UR, Ruzicka T, Tyring SK, Stuschke M, Roggendorf M, Schwartz RA, et al. Update on Kaposi's sarcoma and other HHV8 associated diseases. part 2: pathogenesis, Castleman's disease, and pleural effusion lymphoma. Lancet Infect Dis. 2002;2:344–352
  15. Iwai H, Nakae K, Ikeda K, Ogura M, Miyamoto M, Omae M, et al. Kimura disease: diagnosis and prognostic factors. Otolaryngol Head Neck Surg. 2007;137:306–311
  16. Izumi KM, McFarland EC, Riley EA, Rizzo D, Chen Y, Kieff E. The residues between the two transformation effector sites of Epstein-Barr virus latent membrane protein 1 are not critical for B-lymphocyte growth transformation. J Virol. 1999;73:9908–9916
  17. Jang KA, Ahn SJ, Choi JH, Sung KJ, Moon KC, Koh JK, et al. Polymerase chain reaction (PCR) for human herpesvirus 8 and heteroduplex PCR for clonality assessment in angiolymphoid hyperplasia with eosinophilia and Kimura's disease. J Cutan Pathol. 2001;28:363–367
  18. Jin YT, Tsai ST, Yan JJ, Hsiao JH, Lee YY, Su IJ. Detection of Kaposi's sarcoma-associated herpesvirus-like DNA sequence in vascular lesions. A reliable diagnostic marker for Kaposi's sarcoma. Am J Clin Pathol. 1996;105:360–363
  19. Katagiri K, Itami S, Hatano Y, Yamaguchi T, Takaysu S. In vivo expression of IL-4, IL-5, IL-13 and IFN-gamma mRNAs in peripheral blood mononuclear cells and effect of cyclosporin A in a patient with Kimura's disease. Br J Dermatol. 1997;137:972–977
  20. Kazakov DV, Prinz BM, Michaelis S, Schmid M, Müller B, Adams V, et al. Study of HHV-8 DNA sequences in archival biopsies from lesional skin of Kaposi's sarcoma, various mesenchymal tumors and related reactive conditions. J Cutan Pathol. 2002;29:279–281
  21. Kim HT, Szeto C. Eosinophilic hyperplastic lymphogranuloma, comparison with Mikulicz's disease. Chin Med J. 1937;23:699–700
  22. Kimura T, Voshimura S, Ishikawa E. On the unusual granulation combined with hyperplastic changes of lymphatic tissues. Trans Soc Pathol Jpn. 1948;37:170–180
  23. Kimura Y, Pawankar R, Aoki M, Niimi Y, Kawana S. Mast cells and T cells in Kimura's disease express increased levels of interleukin-4, interleukin-5, eotaxin and RANTES. Clin Exp Allergy. 2002;32:1787–1793
  24. Kuwana M, Okazaki Y, Kodama H, Satoh T, Kawakami Y, Ikeda Y. Endothelial differentiation potential of human monocyte-derived multipotential cells. Stem Cells. 2006;24:2733–2743
  25. Leenman EE, Panzer-Grümayer RE, Fischer S, Leitch HA, Horsman DE, Lion T, et al. Rapid determination of Epstein-Barr virus latent or lytic infection in single human cells using in situ hybridization. Mod Pathol. 2004;17:1564–1572
  26. Meningaud JP, Pitak-Arnnop P, Fouret P, Bertrand JC. Kimura's disease of the parotid region: report of 2 cases and review of the literature. J Oral Maxillofac Surg. 2007;65:134–140
  27. Nogore E, Llorca J, Sánchez-Motilla JM, Ledesma E, Fortea JM, Aliaga A. Detection of Epstein-Barr virus DNA in a patient with Kimura's disease. Int J Dermatol. 2000;39:618–620
  28. Ouhtit A, Gaur RL, Abd Elmageed ZY, Fernando A, Thouta R, Trappey AK, et al. Towards understanding the mode of action of the multifaceted cell adhesion receptor CD146. Biochim Biophys Acta. 2009;1795:130–136
  29. Peichev M, Naiyer AJ, Pereira D, Zhu Z, Lane WJ, Williams M, et al. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood. 2000;95:952–958
  30. Peris K, Niedermeyer H, Cerroni L, Radaskiewicz T, Chimenti S, Höfler H. Detection of Epstein-Barr virus genome in primary cutaneous T and B cell lymphomas and pseudolymphomas. Arch Dermatol Res. 1994;286:364–368
  31. Pigozzi B, Bordignon M, Belloni Fortina A, Michelotto G, Alaibac M. Expression of the CD1a molecule in B- and T-lymphoproliferative skin conditions. Oncol Rep. 2006;15:347–351
  32. Rajpoot DK, Pahl M, Clark J. Nephrotic syndrome associated with Kimura disease. Pediatr Nephrol. 2000;14:486–488
  33. Sauter B, Foedinger D, Sterniczky B, Wolff K, Rappersberger K. Immunoelectron microscopic characterization of human dermal lymphatic microvascular endothelial cells. Differential expression of CD31, CD34, and type IV collagen with lymphatic endothelial cells vs blood capillary endothelial cells in normal human skin, lymphangioma, and hemangioma in situ. J Histochem Cytochem. 1998;46:165–176
  34. Tabata H, Ishikawa O, Ohnishi K, Ishikawa H. Kimura's disease with marked proliferation of HLA-DR+CD4+ T cells in the skin, node and peripheral blood. Dermatology. 1992;184:145–148
  35. Terada N, Konno A, Shirotori K, Fujisawa T, Atsuta J, Ichimi R, et al. Mechanism of eosinophil infiltration in the patient with subcutaneous angioblastic lymphoid hyperplasia with eosinophilia (Kimura's disease). Mechanism of eosinophil chemotaxis mediated by candida antigen and IL-5. Int Arch Allergy Immunol. 1994;104(Suppl 1):18–20
  36. Viswanatha B. Kimura's disease in children: a 9 years prospective study. Int J Pediatr Otorhinolaryngol. 2007;71:1521–1525
  37. Yamada A, Mitsuhashi K, Miyakawa Y, Kosaka K, Takehara K, Iijima M, et al. Membranous glomerulonephritis associated with eosinophilic lymphfolliculosis of the skin (Kimura's disease): report of a case and review of the literature. Clin Nephro. 1982;18:211–215

☆ Presented at the 20th European Congress of Pathology, Paris, France, on September 3-8, 2005, with updated information; dedicated to Prof. Jacques-Charles Bertrand on the occasion of his 65th birthday.Funding: There was no grant support for this study.

PII: S1010-5182(09)00157-7

doi: 10.1016/j.jcms.2009.08.001

Journal of Cranio-Maxillo-Facial Surgery
Volume 38, Issue 4 , Pages 266-270 , June 2010

Article Tools