3D powder printed calcium phosphate implants for reconstruction of cranial and maxillofacial defects

Klammert, Uwe; Gbureck, Uwe; Vorndran, Elke; Rödiger, Jan; Meyer-Marcotty, Philipp; Kübler, Alexander C.

doi:10.1016/j.jcms.2010.01.009

« Previous Next »Journal of Cranio-Maxillo-Facial Surgery
Volume 38, Issue 8 , Pages 565-570, December 2010

3D powder printed calcium phosphate implants for reconstruction of cranial and maxillofacial defects

Uwe Klammert
- Department of Cranio-Maxillo-Facial Surgery (Head: Prof. Dr. Dr. Alexander C. Kübler), University of Würzburg, Pleicherwall 2, 97070 Würzburg, Germany
- Uwe KLAMMERT, University of Würzburg, Department of Cranio-Maxillo-Facial Surgery, Pleicherwall 2, 97070 Würzburg, Germany. Tel.: +49 931 201 74845
Uwe Gbureck
- Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Pleicherwall 2, 97070 Würzburg, Germany
Elke Vorndran
- Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Pleicherwall 2, 97070 Würzburg, Germany
Jan Rödiger
- Department of Cranio-Maxillo-Facial Surgery (Head: Prof. Dr. Dr. Alexander C. Kübler), University of Würzburg, Pleicherwall 2, 97070 Würzburg, Germany
Philipp Meyer-Marcotty
- Department of Orthodontics (Head: Prof. Dr. Angelika Stellzig-Eisenhauer), University of Würzburg, Pleicherwall 2, 97070 Würzburg, Germany
Alexander C. Kübler
- Department of Cranio-Maxillo-Facial Surgery (Head: Prof. Dr. Dr. Alexander C. Kübler), University of Würzburg, Pleicherwall 2, 97070 Würzburg, Germany

Received 8 July 2009; accepted 26 January 2010. published online 08 March 2010.

Summary

Background

The aim of this study was to investigate the processing and the possible use of 3D powder printed calcium phosphate implants for the reconstruction of cranial and maxillofacial defects.

Materials

The fabrication of the implants was carried out with a commercial 3D powder printing system. Diluted phosphoric acid was printed onto tricalcium phosphate powder, leading to the formation of dicalcium phosphate dihydrate (Brushite). Hydrothermal conversion of the brushite matrices led to the formation of dicalcium phosphate anhydrous (Monetite).

Method

Bony defects were generated using a human cadaver skull. The implants were computer-aided designed (CAD) using a mirror imaging procedure following computed tomography of the skull. Specific implants were manufactured by the 3D powder printing rapid prototyping technique.

Result

The processing chain from data acquisition to printing of the implants proved to be practical and uncomplicated. The individual implants showed a high degree of accuracy of fit. Mechanical and physical investigations revealed suitable characteristics.

Conclusion

3D powder printing of calcium phosphate cement material provides a promising new method for the manufacturing of biodegradable synthetic patient-specific craniofacial implants.

Keywords: bone replacement material, brushite, monetite, 3D powder printing, cranioplasty