Parry–Romberg syndrome: volumetric regeneration by structural fat grafting technique

Summary 

The use of adipose tissue transfer for correction of maxillo-facial defects was reported for the first time at the end of the 19th century and has since been the subject of numerous studies.

Structural Fat Grafting (SFG) differs from other fat grafting techniques in both the harvesting and placement of the fat. The main indications for SFG are for the restoration and rejuvenation of the face. Recent applications include the correction of localised tissue atrophy, loss of substance due to trauma, post-tumour, congenital complex craniofacial deformities, burns, and hemifacial atrophy.

The authors describe a case of a 20-year-old woman with right Parry–Romberg syndrome (PRS) treated over many years with many different surgical reconstructive techniques with poor results. After five SFG (three complete procedures and two minor revisions) over three years, the authors obtained a good aesthetic result with complete patient satisfaction.

SFG can be an excellent technique for facial reconstruction and re-contouring, with natural and long-lasting results.

Keywords: Parry–Romberg syndrome, facial lipoatrophy, facial reconstruction, lipostructure, stem cells